Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic assessment of galanin overexpressing and galanin receptor R1 knockout mice in the tail suspension test for depression-related behavior.

Psychopharmacology - 1 Mar 2005

Holmes Andrew, Li Qian, Koenig Elizabeth A, Gold Eric, Stephenson Dejaimenay, Yang Rebecca J, Dreiling Jennifer, Sullivan Tim, Crawley Jacqueline N

Abstract excerpt

RATIONALE: Galanin and its receptors exert inhibitory neuromodulatory control over brain monoamines. Rat studies revealed that galanin expression is upregulated by exposure to stressors and that galanin manipulations modify neuroendocrine and behavioral responses to stress, leading to the hypothesis that galanin mediates depression-related behaviors. METHODS: In the present study, we examined the role of galanin...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoradiography
Share to Depression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fluoxetine

Share to Galanin

Share to Injections, Intraventricular

Share to Mice, Transgenic

Share to Motor Activity

Share to Selective Serotonin Reuptake Inhibitors

Source

Identifiers

PMID: 15365683
DOI: 10.1007/s00213-004-1997-1

Genes

GAL
TST
HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic assessment of galanin overexpressing and galanin receptor R1 knockout mice in the tail suspension test for depression-related behavior.PMID 15365683Read ↗

Phenotypic analysis of GalR2 knockout mice in anxiety- and depression-related behavioral tests.Semantic proximity Read ↗

GAL3 receptor KO mice exhibit an anxiety-like phenotype.Semantic proximity Read ↗

Evaluation of an anxiety-related phenotype in galanin overexpressing transgenic mice.Semantic proximity Read ↗

Galanin receptor 2 overexpressing mice display an antidepressive-like phenotype: possible involvement of the subiculum.Semantic proximity Read ↗

Elimination of galanin synthesis in noradrenergic neurons reduces galanin in select brain areas and promotes active coping behaviorsSemantic proximity Read ↗

Neurochemical and behavioral alterations in glucocorticoid receptor-impaired transgenic mice after chronic mild stress.Semantic proximity Read ↗

Elevated anxiety and antidepressant-like responses in serotonin 5-HT1A receptor mutant mice.Semantic proximity Read ↗

Galanin receptor subtype 2 (GalR2) null mutant mice display an anxiogenic-like phenotype specific to the elevated plus-maze.Semantic proximity Read ↗

Investigating anxiety and depressive-like phenotypes in genetic mouse models of serotonin depletion.Semantic proximity Read ↗

Neuroendocrine profiles in galanin-overexpressing and knockout mice.Semantic proximity Read ↗

The neuropeptide galanin and variants in the GalR1 gene are associated with nicotine dependence.Semantic proximity Read ↗

Behavioural characterisation of young adult transgenic mice overexpressing galanin under the PDGF-B promoter.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.