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Article

Galanin receptor subtype 2 (GalR2) null mutant mice display an anxiogenic-like phenotype specific to the elevated plus-maze.

Pharmacology, biochemistry, and behavior - 1 Jan 2007

Bailey Kathleen R, Pavlova Maria N, Rohde Alex D, Hohmann John G, Crawley Jacqueline N

Abstract excerpt

The neuropeptide galanin has been implicated in anxiety-related behaviors, cognition, analgesia, and feeding in rodents. Neuromodulatory actions of galanin are mediated by three G-protein coupled receptors, GalR1, GalR2, and GalR3. The present study investigates the role of the GalR2 receptor by evaluating behavioral phenotypes of mice with a targeted mutation in the GalR2 gene. A three-tiered behavioral...

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Identifiers

PMID: 17257664
DOI: 10.1016/j.pbb.2006.11.024
PMCID: PMC1853242

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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