Article
SNP combinations in chromosome-wide genes are associated with bone mineral density in Taiwanese women.
The Chinese journal of physiology - 29 Feb 2008
Lin Gau-Tyan, Tseng Hung-Fu, Chang Chen-Kang, Chuang Li-Yeh, Liu Chih-Shan, Yang Cheng-Hong, Tu Chung-Jui, Wang Eng-Chi, Tan Hsiu-Fen, Chang Chia-Che, Wen Cheng-Hao, Chen Hsiang-Chi, Chang Hsueh-Wei
Abstract excerpt
Osteoporosis is a major public health problem, mainly quantified by low BMD. Eleven polymorphisms were investigated in this study; TNFalpha-857 (rs1799724), TGFbeta1-509 (rs1800469), osteocalcin (rs1800247), TNFalpha-308 (rs1800629), PTH BstB I (rs6254), PTH Dra II (), IL-1ra (VNTR), HSP70 hom (), HSP 70-2 (), CTR (), and BMP-4 (). The relationship between the combined...