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Article

IL1R2 polymorphisms and their interaction are associated with osteoporosis susceptibility in the Chinese Han population.

International journal of immunogenetics - 1 Dec 2021

Rong Kai, Liang Zhiquan, Xiang Wenyuan, Wang Zhan, Wen Fengli, Lu Laijin

Abstract excerpt

AIMS: Interleukin 1 (IL-1) inhibitory receptor type 2 (IL1R2) serves as a negative regulator of IL-1 signalling and is involved in the pathogenesis of osteoporosis. This study aimed to determine the correlation between IL1R2 polymorphism and osteoporosis susceptibility in the Chinese Han population. METHODS: We recruited 594 osteoporosis patients and 599 healthy controls. Six single nucleotide polymorphisms...

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PMID: 34664761
DOI: 10.1111/iji.12547

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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