Article
Multiple osteoporosis susceptibility genes on chromosome 1p36 in Chinese.
Bone - 1 May 2009
Huang Qing-Yang, Li Gloria H Y, Kung Annie W C
Abstract excerpt
INTRODUCTION: Chromosome 1p36 is a region that has previously shown good evidence of linkage to bone mineral density (BMD) in multiple studies, but the genes that are responsible for the linkage signals are unknown. MATERIALS AND METHODS: We performed a gene-wide and tag SNP-based association study of four positional and functional candidate genes (TNFRSF1B, PLOD, CNR2, and MTHFR) at 1p36 in 1, 243 case-control...
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