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Article

Association of TGF-β1 and IL-10 Gene Polymorphisms with Osteoporosis in a Study of Taiwanese Osteoporotic Patients.

Genes - 18 Jun 2021

Tu Min-Yu, Han Kuei-Yang, Lan Ying-Wei, Chang Ku-Yi, Lai Cheng-Wei, Staniczek Theresa, Lai Chung-Yu, Chong Kowit-Yu, Chen Chuan-Mu

Abstract excerpt

Osteoporosis is a rising health threat in the increasingly aging world population. It is a common skeletal disease strongly linked to genetic predisposition. We aim to identify the effects of the anti-inflammatory TGF-β1- and IL-10-specific single-nucleotide polymorphism (SNP) combination on the risk for osteoporosis. We investigated and analyzed the relationships between three TGF-β1 SNPs (-509C/T, +869 T/C and...

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Identifiers

PMID: 34207210
DOI: 10.3390/genes12060930
PMCID: PMC8233820

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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