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Article

Abdominal obesity and hyperglycemia mask the effect of a common APOC3 haplotype on the risk of myocardial infarction.

The American journal of clinical nutrition - 1 Jun 2008

Ruiz-Narváez Edward A, Sacks Frank M, Campos Hannia

Abstract excerpt

BACKGROUND: Plasma apolipoprotein (apo) C-III strongly predicts myocardial infarction (MI) and directly activates atherogenic processes in vascular cells. Genetic variation in the insulin response element of the APOC3 promoter is associated with an increased risk of MI. OBJECTIVE: The objective was to determine whether the APOC3 promoter variation affects plasma apo C-III concentrations and MI only when insulin...

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Source

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Identifiers

PMID: 18541587
DOI: 10.1093/ajcn/87.6.1932
PMCID: PMC3861874

Genes

APOC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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