Association between the -455T>C promoter polymorphism of the APOC3 gene and the metabolic syndrome in a multi-ethnic sample.

doi:10.1186/1471-2350-8-80

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Article

Association between the -455T>C promoter polymorphism of the APOC3 gene and the metabolic syndrome in a multi-ethnic sample.

BMC medical genetics - 20 Dec 2007

Pollex Rebecca L, Ban Matthew R, Young T Kue, Bjerregaard Peter, Anand Sonia S, Yusuf Salim, Zinman Bernard, Harris Stewart B, Hanley Anthony J G, Connelly Philip W, Huff Murray W, Hegele Robert A

Abstract excerpt

BACKGROUND: Common polymorphisms in the promoter of the APOC3 gene have been associated with hypertriglyceridemia and may impact on phenotypic expression of the metabolic syndrome (MetS). The rs7566605 marker, located near the INSIG2 gene, has been found to be associated with obesity, making it also a potential genetic determinant for MetS. The objective of this study is to examine the APOC3 -455T>C and the...

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Identifiers

PMID: 18096054
DOI: 10.1186/1471-2350-8-80
PMCID: PMC2241585

Genes

APOC3
INSIG2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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