Article
9p21.3 Coronary Artery Disease Locus Identifies Patients With Treatment Benefit From Bariatric Surgery in the Nonrandomized Prospective Controlled Swedish Obese Subjects Study.
Circulation. Genomic and precision medicine - 1 Oct 2020
Jacobson Peter, Peltonen Markku, Svensson Per-Arne, Taube Magdalena, Andersson-Assarsson Johanna C, Sjoholm Kajsa, Bouchard Claude, Carlsson Björn, Carlsson Lena M S
Abstract excerpt
BACKGROUND: Sequence variation at chromosome 9p21.3 accounts for 20% of myocardial infarctions (MIs) in several populations. Whereas the risk conferred by the 9p21.3 locus appears to act independently of traditional risk factors, studies suggest that the association between 9p21.3 and MI is modified by glucose homeostasis and lifestyle. We examined if the 9p21.3 variant rs1333049, along with the previously...
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