Dissociation between APOC3 variants, hepatic triglyceride content and insulin resistance.

doi:10.1002/hep.24072

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Article

Dissociation between APOC3 variants, hepatic triglyceride content and insulin resistance.

Hepatology (Baltimore, Md.) - 1 Feb 2011

Kozlitina Julia, Boerwinkle Eric, Cohen Jonathan C, Hobbs Helen H

Abstract excerpt

UNLABELLED: Nonalcoholic fatty liver disease (NAFLD) is an escalating health problem that is frequently associated with obesity and insulin resistance. The mechanistic relationship between NAFLD, obesity, and insulin resistance is not well understood. A nonsynonymous variant in patatin-like phospholipase domain containing 3 (rs738409, I148M) has been reproducibly associated with increased hepatic triglyceride...

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Identifiers

PMID: 21274868
DOI: 10.1002/hep.24072
PMCID: PMC3057507

Genes

APOC3

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Dissociation between APOC3 variants, hepatic triglyceride content and insulin resistance.PMID 21274868Read ↗

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