Article
The -1131 T>C and S19W APOA5 gene polymorphisms are associated with high levels of triglycerides and apolipoprotein C-III, but not with coronary artery disease: an angiographic study.
Atherosclerosis - 1 Apr 2007
Martinelli Nicola, Trabetti Elisabetta, Bassi Antonella, Girelli Domenico, Friso Simonetta, Pizzolo Francesca, Sandri Marco, Malerba Giovanni, Pignatti Pier Franco, Corrocher Roberto, Olivieri Oliviero
Abstract excerpt
High plasma concentrations of triglycerides (TG) and apolipoprotein C-III (ApoC-III) are well-known risk factors for cardiovascular disease. Two variants of the recently discovered APOA5, 1131 C>T and S19W, have been associated with hypertriglyceridemia, whereas their relation with coronary artery disease (CAD) remains controversial. Nine hundred and thirteen angiografically defined patients (669 CAD and 244...
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