Article
Cystic kidney gene seahorse regulates cilia-mediated processes and Wnt pathways.
Developmental cell - 1 Jun 2008
Kishimoto Norihito, Cao Ying, Park Alice, Sun Zhaoxia
Abstract excerpt
Recently the cilium has emerged as an important sensory organelle for a wide range of cell types in vertebrates. However, the signaling cascade that links ciliary signals to cellular events remains poorly understood. Here, we show that the zebrafish cystic kidney gene seahorse is closely associated with ciliary functions: seahorse is required for establishing left-right asymmetry and for preventing kidney cyst...
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