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Article

Forward genetics uncovers Transmembrane protein 107 as a novel factor required for ciliogenesis and Sonic hedgehog signaling.

Developmental biology - 15 Aug 2012

Christopher Kasey J, Wang Baolin, Kong Yong, Weatherbee Scott D

Abstract excerpt

Cilia are dynamic organelles that are essential for a vast array of developmental patterning events, including left-right specification, skeletal formation, neural development, and organogenesis. Despite recent advances in understanding cilia form and function, many key ciliogenesis components have yet to be identified. By using a forward genetics approach, we isolated a novel mutant allele (schlei) of the mouse...

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Identifiers

PMID: 22698544
DOI: 10.1016/j.ydbio.2012.06.008
PMCID: PMC3402655

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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