Multiple functions for Pax6 in mouse eye and nasal development.

doi:10.1101/gad.10.4.435

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Article

Multiple functions for Pax6 in mouse eye and nasal development.

Genes & development - 15 Feb 1996

Quinn J C, West J D, Hill R E

Abstract excerpt

Mouse embryos, homozygous for the small eye (Sey) mutation die soon after birth with severe facial abnormalities that result from the failure of the eyes and nasal cavities to develop. Mutations in the Pax6 gene are responsible for the Sey phenotype. As a general disruption of eye and nasal devel...

Topics

Animals
Base Sequence
Chimera
DNA Primers
DNA-Binding Proteins
Eye
Eye Proteins
Gene Expression Regulation, Developmental
Genetic Markers
Genotype
Homeodomain Proteins
Homozygote
In Situ Hybridization
Lens, Crystalline
Mice
Mice, Inbred BALB C
Mice, Transgenic
Molecular Sequence Data

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