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Article

The role of Pax-6 in eye and nasal development.

Development (Cambridge, England) - 1 May 1995

Grindley J C, Davidson D R, Hill R E

Abstract excerpt

Small eye (Sey) mice homozygous for mutations in the Pax-6 gene have no lenses and no nasal cavities. We have examined the ontogeny of eye and nasal defects in Sey/Sey embryos and have related the defects seen to the pattern of Pax-6 mRNA expression in the mouse during normal eye and nasal develo...

Topics

Animals
Base Sequence
Cell Death
DNA-Binding Proteins
Ectoderm
Eye
Eye Proteins
Homeodomain Proteins
In Situ Hybridization
Lens, Crystalline
Mice
Mice, Mutant Strains
Mice, Transgenic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Morphogenesis

Nose

Oligonucleotide Probes

PAX6 Transcription Factor

Source

Identifiers

PMID: 7789273
DOI: 10.1242/dev.121.5.1433

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7789273-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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