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Article

The role of Pax-6 in eye and nasal development.

Development (Cambridge, England) - 1 May 1995

Grindley J C, Davidson D R, Hill R E

Abstract excerpt

Small eye (Sey) mice homozygous for mutations in the Pax-6 gene have no lenses and no nasal cavities. We have examined the ontogeny of eye and nasal defects in Sey/Sey embryos and have related the defects seen to the pattern of Pax-6 mRNA expression in the mouse during normal eye and nasal development. There are two principal components of the early eye, the neural ectoderm of the optic vesicle, which forms the...

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Identifiers

PMID: 7789273
DOI: 10.1242/dev.121.5.1433

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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