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Article

The exocyst is required for photoreceptor ciliogenesis and retinal development.

The Journal of biological chemistry - 8 Sept 2017

Lobo Glenn P, Fulmer Diana, Guo Lilong, Zuo Xiaofeng, Dang Yujing, Kim Seok-Hyung, Su Yanhui, George Kola, Obert Elisabeth, Fogelgren Ben, Nihalani Deepak, Norris Russell A, Rohrer Bärbel, Lipschutz Joshua H

Abstract excerpt

We previously have shown that the highly conserved eight-protein exocyst trafficking complex is required for ciliogenesis in kidney tubule cells. We hypothesized here that ciliogenic programs are conserved across organs and species. To determine whether renal primary ciliogenic programs are conserved in the eye, and to characterize the function and mechanisms by which the exocyst regulates eye development in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Inbred C57BL

Share to Photoreceptor Cells, Vertebrate

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Source

Open in PubMed Open full text

Identifiers

PMID: 28729419
DOI: 10.1074/jbc.M117.795674
PMCID: PMC5592663

Genes

EXOC5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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