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Article

Nephrocystin-3 is required for ciliary function in zebrafish embryos.

American journal of physiology. Renal physiology - 1 Jul 2010

Zhou Weibin, Dai Julie, Attanasio Massimo, Hildebrandt Friedhelm

Abstract excerpt

Nephronophthisis (NPHP) is the most frequent genetic cause of end-stage renal failure in the first three decades of life. It is characterized primarily by renal cysts with extrarenal involvements of the eye and brain. Ten recessive genes responsible for NPHP have been identified by positional cloning. This discovery supported a unifying theory of renal cystic disease, which states that all proteins mutated in...

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Source

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Identifiers

PMID: 20462968
DOI: 10.1152/ajprenal.00043.2010
PMCID: PMC2904175

Genes

NPHP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Nephrocystin-3 is required for ciliary function in zebrafish embryos.PMID 20462968Read ↗

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Mutations in a novel gene, NPHP3, cause adolescent nephronophthisis, tapeto-retinal degeneration and hepatic fibrosis.Semantic proximity Read ↗

Novel NEK8 Mutations Cause Severe Syndromic Renal Cystic Dysplasia through YAP Dysregulation.Semantic proximity Read ↗

Renal Tubule-Specific Deletion of Nephrocystin 3 (Nphp3) Causes Infantile Nephronophthisis-like Phenotypes in Mice.Semantic proximity Read ↗

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