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Gene polymorphisms of the NOD-2/CARD-15 gene and the risk of gastric cancer in Germany.

Anticancer research - 1 Jan 2000

Wex Thomas, Ebert Matthias P A, Kropf Siegfried, Dierkes Jutta, Schüttler Katrin, Röcken Christoph, Höcker Michael, Malfertheiner Peter

Abstract excerpt

BACKGROUND: NOD-2 is involved in the intracellular recognition of bacterial muramyl dipeptides, and three independent polymorphisms of this gene have been identified as risk factors for the development of Crohn's disease. PATIENTS AND METHODS: To study the role of NOD-2 in gastric carcinogenesis, NOD-2 mutations (SNP5: P268S, SNP8: R702W, SNP12: G908R, and SNP13: 3020insC) were genotyped in 171 patients with...

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PMID: 18507017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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