Article
NOD2/CARD15 gene polymorphisms and Crohn's disease in the Chinese population.
Alimentary pharmacology & therapeutics - 15 Jun 2003
Leong R W L, Armuzzi A, Ahmad T, Wong M L, Tse P, Jewell D P, Sung J J Y
Abstract excerpt
BACKGROUND: Crohn's disease affects people world-wide, but the incidence in Asia is lower than in Western countries. This difference may be due to genetic and/or environmental factors. Three single nucleotide polymorphisms (SNPs) of the NOD2/CARD15 gene have been identified to be independently associated with the development of Crohn's disease in Caucasians. Whether these SNPs are involved in the pathogenesis of...
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