Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Toll-like receptor 4 and NOD2/CARD15 mutations in Hungarian patients with Crohn's disease: phenotype-genotype correlations.

World journal of gastroenterology - 14 Mar 2005

Lakatos Peter Laszlo, Lakatos Laszlo, Szalay Ferenc, Willheim-Polli Claudia, Osterreicher Christoph, Tulassay Zsolt, Molnar Tamas, Reinisch Walter, Papp Janos, Mozsik Gyula, Ferenci Peter

Abstract excerpt

AIM: To determine common NOD2/CARD15 mutations and TLR4 D299G polymorphism in Hungarian patients with CD. METHODS: A total of 527 unrelated patients with CD (male/female: 265/262, age: 37.1 (SD 7.6) years) and 200 healthy subjects were included. DNA was screened for possible NOD2/CARD15 mutations by denaturing high-performance liquid chromatography (confirmed by direct sequencing). TLR4 D299G was tested by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Crohn Disease
Share to Hungary

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Intracellular Signaling Peptides and Proteins

Share to Membrane Glycoproteins

Share to Nod2 Signaling Adaptor Protein

Share to Receptors, Cell Surface

Share to Toll-Like Receptor 4

Share to Toll-Like Receptors

Source

Open in PubMed Open full text

Identifiers

PMID: 15770725
DOI: 10.3748/wjg.v11.i10.1489
PMCID: PMC4305691

Genes

NOD2
TLR4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Toll-like receptor 4 and NOD2/CARD15 mutations in Hungarian patients with Crohn's disease: phenotype-genotype correlations.PMID 15770725Read ↗

NOD2/CARD15 mutations in Croatian patients with Crohn's disease: prevalence and genotype-phenotype relationship.Semantic proximity Read ↗

NOD2/CARD15 mutations in Polish and Bosnian populations with and without Crohn's disease: prevalence and genotype-phenotype analysis.Semantic proximity Read ↗

[NOD2/CARD15 mutations and genotype-phenotype correlations in patients with Crohn's disease. Hungarian multicenter study].Semantic proximity Read ↗

Clinical significance of NOD2/CARD15 and Toll-like receptor 4 gene single nucleotide polymorphisms in inflammatory bowel disease.Semantic proximity Read ↗

Crohn's disease is associated with polymorphism of CARD15/NOD2 gene in a Hungarian population.Semantic proximity Read ↗

NOD2/CARD15, TLR4 and CD14 mutations in Scottish and Irish Crohn's disease patients: evidence for genetic heterogeneity within Europe?Semantic proximity Read ↗

NOD2/CARD15 gene polymorphism in patients with inflammatory bowel disease: is Hungary different?Semantic proximity Read ↗

NOD2/CARD15 gene polymorphisms in Crohn's disease: a genotype- phenotype analysis.Semantic proximity Read ↗

Prevalence of mutations of the NOD2/CARD15 gene and relation to phenotype in Spanish patients with Crohn disease.Semantic proximity Read ↗

NOD2/CARD15 and Toll-like 4 receptor gene polymorphism in Chilean patients with inflammatory bowel disease.Semantic proximity Read ↗

Association of NOD2/CARD15 mutations on Crohn's disease phenotype in an Italian population.Semantic proximity Read ↗

Association of NOD2/CARD15 variants with Crohn's disease in a Greek population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.