Localization of genomic regions specific for the attenuated, mouse-adapted poliovirus type 2 strain W-2.

doi:10.1099/0022-1317-71-1-43

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Article

Localization of genomic regions specific for the attenuated, mouse-adapted poliovirus type 2 strain W-2.

The Journal of general virology - 1 Jan 1990

Pevear D C, Oh C K, Cunningham L L, Calenoff M, Jubelt B

Abstract excerpt

In order to begin to elucidate the genomic basis of the attenuation of mouse-adapted, poliovirus type 2 strain W-2 (PV2/W-2), we have cloned and sequenced the virus and compared it with the virulent, mouse-adapted PV2/Lansing strain. In addition, we have performed computer-generated comparisons o...

Topics

Amino Acid Sequence
Animals
Base Sequence
Cloning, Molecular
DNA, Viral
Mice
Molecular Sequence Data
Mutation
Poliovirus
Poliovirus Vaccine, Inactivated
Poliovirus Vaccine, Oral
RNA, Viral
Restriction Mapping
Vaccines, Attenuated

Source

Open in PubMed

Identifiers

PMID: 2154539
DOI: 10.1099/0022-1317-71-1-43

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2154539-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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