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Article

Localization of genomic regions specific for the attenuated, mouse-adapted poliovirus type 2 strain W-2.

The Journal of general virology - 1 Jan 1990

Pevear D C, Oh C K, Cunningham L L, Calenoff M, Jubelt B

Abstract excerpt

In order to begin to elucidate the genomic basis of the attenuation of mouse-adapted, poliovirus type 2 strain W-2 (PV2/W-2), we have cloned and sequenced the virus and compared it with the virulent, mouse-adapted PV2/Lansing strain. In addition, we have performed computer-generated comparisons of PV2/W-2 to the non-mouse-adapted, attenuated PV2/Sabin strain to determine whether mutational patterns occur that...

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Identifiers

PMID: 2154539
DOI: 10.1099/0022-1317-71-1-43

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