Article
Poliovirus variants selected on mutant receptor-expressing cells identify capsid residues that expand receptor recognition.
Journal of virology - 1 Aug 1995
Colston E M, Racaniello V R
Abstract excerpt
Mutations in the predicted C'-C"-D edge of the first immunoglobulin-like domain of the poliovirus receptor were previously shown to eliminate poliovirus binding. To identify capsid residues that expand receptor recognition, 16 poliovirus suppressor mutants were selected that replicate in three di...
Topics
- Adaptation, Physiological
- Animals
- Capsid
- HeLa Cells
- Humans
- Mice
- Mutation
- Poliovirus
- Receptors, Virus
