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Article

MMP-2 geno-phenotype is prognostic for colorectal cancer survival, whereas MMP-9 is not.

British journal of cancer - 3 Jun 2008

Langers A M J, Sier C F M, Hawinkels L J A C, Kubben F J G M, van Duijn W, van der Reijden J J, Lamers C B H W, Hommes D W, Verspaget H W

Abstract excerpt

The prognostic significance of single-nucleotide polymorphisms (SNPs) and tumour protein levels of MMP-2 and MMP-9 was evaluated in 215 colorectal cancer patients. Single-nucleotide polymorphism MMP-2(-1306T) and high MMP-2 levels were significantly associated with worse survival. Extreme tumour MMP-9 levels were associated with poor prognosis but SNP MMP-9(-1562C>T) was not. Tumour MMP levels were not determined...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 18506186
DOI: 10.1038/sj.bjc.6604380
PMCID: PMC2410128

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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