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Article

Genetic polymorphisms of matrix metalloproteinases and clinical outcomes in colorectal cancer patients.

International journal of medical sciences - 1 Jan 2013

Ting Wen-Chien, Chen Lu-Min, Pao Jiunn-Bey, Yang Ying-Pi, You Bang-Jau, Chang Ta-Yuan, Lan Yu-Hsuan, Lee Hong-Zin, Bao Bo-Ying

Abstract excerpt

BACKGROUND: Colorectal cancer metastasis is a multistep process involving degradation of extracellular matrix components by proteolytic enzymes. Among them, matrix metalloproteinases (MMPs) are the principal degrading enzymes and their expressions/activities are also correlated with survival. Much research has showed the associations between genetic polymorphisms in MMPs and risk of colorectal cancer; however,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23801889
DOI: 10.7150/ijms.6686
PMCID: PMC3691801

Genes

MMP2

Provenance

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