Article
MMP-2 and MMP-9 in normal mucosa are independently associated with outcome of colorectal cancer patients.
British journal of cancer - 24 Apr 2012
Langers A M J, Verspaget H W, Hawinkels L J A C, Kubben F J G M, van Duijn W, van der Reijden J J, Hardwick J C H, Hommes D W, Sier C F M
Abstract excerpt
BACKGROUND: Upregulation of the matrix metalloproteinases MMP-2 and MMP-9 in various cancers has been associated with worse survival of the patients. METHODS: We assessed MMP-2 and MMP-9 levels in normal colorectal mucosa from colorectal cancer patients in relation to the course of the disease. RESULTS: A high protein expression of MMP-2 as well as MMP-9 in normal mucosa was found to be correlated with worse...
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