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Article

The collagenase-1 (MMP-1) gene promoter polymorphism - 1607/2G is associated with favourable prognosis in patients with colorectal cancer.

British journal of cancer - 12 Mar 2007

Hettiaratchi A, Hawkins N J, McKenzie G, Ward R L, Hunt J E, Wakefield D, Di Girolamo N

Abstract excerpt

Matrix metalloproteinase (MMP) overexpression has been implicated in the pathogenesis of colorectal carcinoma (CRC). Accumulating evidence suggests that MMP promoter single nucleotide polymorphisms (SNPs) effecting gene transcription are associated with enhanced susceptibility for the development of malignant disease, increased tumour invasiveness and poor patient survival. The aim of the current investigation...

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Identifiers

PMID: 17311017
DOI: 10.1038/sj.bjc.6603630
PMCID: PMC2360084

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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