Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variants in matrix metalloproteinase genes as disposition factors for ovarian cancer risk, survival, and clinical outcome.

Molecular carcinogenesis - 1 Jun 2015

Wang Yan, Ye Yuanqing, Lin Jie, Meyer Larissa, Wu Xifeng, Lu Karen, Liang Dong

Abstract excerpt

Ovarian cancer is one of the leading female cancers in the United States. Challenges remain in early diagnosis of this deadly disease. Matrix metalloproteinases (MMPs) family genes are paradoxically involved in cancer promotion and suppression. We hypothesize that genetic variants in MMP genes are associated with ovarian cancer development, so they could be potential markers for ovarian cancer diagnosis and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Matrix Metalloproteinases

Share to Ovarian Neoplasms

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Share to Survival Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 25867973
DOI: 10.1002/mc.22111
PMCID: PMC4869714

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variants in matrix metalloproteinase genes as disposition factors for ovarian cancer risk, survival, and clinical outcome.PMID 25867973Read ↗

Association between matrix metalloproteinases polymorphisms and ovarian cancer risk: A meta-analysis and systematic review.Semantic proximity Read ↗

The use of predictive or prognostic genetic biomarkers in endometrial and other hormone-related cancers: justification for extensive candidate gene single nucleotide polymorphism studies of the matrix metalloproteinase family and their inhibitors.Semantic proximity Read ↗

Matrix metalloproteinase genes are associated with breast cancer risk and survival: the Breast Cancer Health Disparities Study.Semantic proximity Read ↗

Genetic polymorphisms of matrix metalloproteinases and clinical outcomes in colorectal cancer patients.Semantic proximity Read ↗

No associations of a set of SNPs in the Vascular Endothelial Growth Factor (VEGF) and Matrix Metalloproteinase (MMP) genes with survival of colorectal cancer patients.Semantic proximity Read ↗

A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2.Semantic proximity Read ↗

Matrix Metalloproteinase Gene Polymorphisms Are Associated with Breast Cancer in the Caucasian Women of Russia.Semantic proximity Read ↗

Matrix metalloproteinase-8 promoter gene polymorphisms in Mexican women with ovarian cancer.Semantic proximity Read ↗

Increased Expression of MMP17 Predicts Poor Clinical Outcomes in Epithelial Ovarian Cancer PatientsSemantic proximity Read ↗

Common matrix metalloproteinase-2 gene variants and altered susceptibility to breast cancer and associated features in Tunisian womenSemantic proximity Read ↗

The functional polymorphisms on promoter region of matrix metalloproteinase-12, -13 genes may alter the risk of epithelial ovarian carcinoma in Chinese.Semantic proximity Read ↗

Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.