Article
Role of Matrix Metallopeptidase-2 Genotypes in Taiwanese Patients With Colorectal Cancer.
Anticancer research - 1 Nov 2022
Yueh Te-Cheng, Hung Yi-Chih, Lee Hsu-Tung, Yang Mei-Due, Wang Zhi-Hong, Yang Ya-Chen, Ke Tao-Wei, Pei Jen-Sheng, Tsai Chia-Wen, Bau DA-Tian, Chang Wen-Shin
Abstract excerpt
BACKGROUND/AIM: Matrix metalloproteinase-2 (MMP2) has been reported to plays a critical role in the metastatic behaviors of cancer via regulation of the extracellular matrix. However, its genotypes have seldom been examined in colorectal cancer (CRC). We examined the role of MMP2 promoter -1306 (rs243865) and -735 (rs2285053) genotypes in colorectal cancer (CRC). MATERIALS AND METHODS: Genotypes of MMP2 were...
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