Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mechanisms of fluoroquinolone resistance in Staphylococcus aureus.

The Journal of infectious diseases - 1 May 1991

Kaatz G W, Seo S M, Ruble C A

Abstract excerpt

Fluoroquinolone resistance that arose in the test strain during ciprofloxacin therapy of experimental Staphylococcus aureus endocarditis was studied. In two isolates, resistance was due to a decreased sensitivity of the process of DNA synthesis to fluoroquinolones, suggesting the presence of an altered DNA gyrase. Another isolate had an enhanced energy-dependent mechanism, possibly an efflux system, by which...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to Cloning, Molecular
Share to DNA, Bacterial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drug Resistance, Microbial

Share to Membrane Proteins

Share to Mutation

Share to Nucleic Acid Hybridization

Share to Restriction Mapping

Source

Identifiers

PMID: 1850442
DOI: 10.1093/infdis/163.5.1080

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mechanisms of fluoroquinolone resistance in Staphylococcus aureus.PMID 1850442Read ↗

Mechanisms of fluoroquinolone resistance in genetically related strains of Staphylococcus aureus.Semantic proximity Read ↗

Mechanisms involved in the development of resistance to fluoroquinolones in Escherichia coli isolates.Semantic proximity Read ↗

Mechanisms of resistance to fluoroquinolones.Semantic proximity Read ↗

Mechanism of quinolone resistance in Staphylococcus aureus.Semantic proximity Read ↗

Novel ciprofloxacin-resistant, nalidixic acid-susceptible mutant of Staphylococcus aureus.Semantic proximity Read ↗

Evidence of an efflux pump in Serratia marcescens.Semantic proximity Read ↗

Mechanisms and spread of fluoroquinolone resistance in Streptococcus pneumoniae.Semantic proximity Read ↗

Mechanisms of resistance to the 4-quinolone antibacterial agents.Semantic proximity Read ↗

Active efflux as a mechanism of resistance to ciprofloxacin in Streptococcus pneumoniae.Semantic proximity Read ↗

A novel locus conferring fluoroquinolone resistance in Staphylococcus aureus.Semantic proximity Read ↗

Substrate specificity and energetics of antiseptic and disinfectant resistance in Staphylococcus aureus.Semantic proximity Read ↗

Role of gyrA mutation and loss of OprF in the multiple antibiotic resistance phenotype of Pseudomonas aeruginosa G49.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.