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Article

Mechanisms of fluoroquinolone resistance in genetically related strains of Staphylococcus aureus.

Antimicrobial agents and chemotherapy - 1 Dec 1997

Kaatz G W, Seo S M

Abstract excerpt

Fluoroquinolone resistance in Staphylococcus aureus results from amino acid substitutions at particular locations in the DNA gyrase A and B subunits as well as in the topoisomerase IV A subunit and from NorA-mediated efflux. More than one resistance mechanism may be present in a single strain. Fluoroquinolone-resistant derivatives of SA-1199, a methicillin-susceptible S. aureus strain, were selected in vivo or in...

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Identifiers

PMID: 9420048
DOI: 10.1128/AAC.41.12.2733
PMCID: PMC164198

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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