Article
Mechanisms of resistance to fluoroquinolones.
The National medical journal of India - 1 Jan 2000
Rattan A
Abstract excerpt
Fluoroquinolones have some of the properties of an 'ideal' anti-microbial agent. Because of their potent broad spectrum activity and absence of transferable mechanism of resistance or inactivating enzymes, it was hoped that clinical resistance to this useful group of drugs would not occur. However, over the years, due to intense selective pressure and relative lack of potency of the available quinolones against...
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