Article
Substrate specificity and energetics of antiseptic and disinfectant resistance in Staphylococcus aureus.
FEMS microbiology letters - 15 Aug 1992
Littlejohn T G, Paulsen I T, Gillespie M T, Tennent J M, Midgley M, Jones I G, Purewal A S, Skurray R A
Abstract excerpt
Clinical isolates of Staphylococcus aureus carry various antiseptic and disinfectant resistance determinants (qac genes) on a variety of plasmids. The biochemistry and specificity of these resistance genes in S. aureus is the subject of this report. The qac genes were separated into two families on the basis of resistance profiles and DNA homology. Isotopic and fluorimetric assays demonstrated that the qac genes...
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