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Article

Evidence of an efflux pump in Serratia marcescens.

Microbial drug resistance (Larchmont, N.Y.) - 1 Jan 2000

Berlanga M, Vázquez J L, Hernandez-Borrell J, Montero M T, Viñas M

Abstract excerpt

Spontaneous mutants resistant to fluoroquinolones were obtained by exposing Serratia marcescens NIMA (wild-type strain) to increasing concentrations of ciprofloxacin both in liquid and on solid media. Frequencies of mutation ranged from 10(-7) to 10(-9). Active expulsion of antibiotic was explored as a possible mechanism of resistance in mutants as well as changes in topoisomerase target genes. The role of...

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Identifiers

PMID: 10990265
DOI: 10.1089/107662900419410

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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