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Article

Mechanisms and spread of fluoroquinolone resistance in Streptococcus pneumoniae.

Research in microbiology - 1 Jan 2000

Varon E, Gutmann L

Abstract excerpt

The development of fluoroquinolones (FQs) with enhanced activity against Streptococcus pneumoniae is a potential advance in the treatment of pneumococcal infections, particularly those due to beta-lactam-resistant pneumococci. However, FQ-resistant clinical isolates selected by the older FQs have already been reported, with mutation(s) in both FQ targets conferring cross-resistance to newer FQs. It is likely that...

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PMID: 10961461
DOI: 10.1016/s0923-2508(00)00167-4

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