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Article

ATM promotes the obligate XY crossover and both crossover control and chromosome axis integrity on autosomes.

PLoS genetics - 23 May 2008

Barchi Marco, Roig Ignasi, Di Giacomo Monica, de Rooij Dirk G, Keeney Scott, Jasin Maria

Abstract excerpt

During meiosis in most sexually reproducing organisms, recombination forms crossovers between homologous maternal and paternal chromosomes and thereby promotes proper chromosome segregation at the first meiotic division. The number and distribution of crossovers are tightly controlled, but the factors that contribute to this control are poorly understood in most organisms, including mammals. Here we provide...

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Share to Ataxia Telangiectasia Mutated Proteins
Share to Chromosome Pairing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Crossing Over, Genetic

Share to Endodeoxyribonucleases

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Source

Open in PubMed Open full text

Identifiers

PMID: 18497861
DOI: 10.1371/journal.pgen.1000076
PMCID: PMC2374915

Genes

ATM
MLH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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