Ku70 and non-homologous end joining protect testicular cells from DNA damage

doi:10.1242/jcs.122788

Article

Ku70 and non-homologous end joining protect testicular cells from DNA damage

15 Jul 2013

Abstract excerpt

Spermatogenesis is a complex process that generates haploid germ cells or spores and implements meiosis, a succession of two special cell divisions that are required for homologous chromosome segregation. During prophase to the first meiotic division, homologous recombination (HR) repairs Spo11-dependent DNA double-strand breaks (DSBs) in the presence of telomere movements to allow for chromosome pairing and...

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