Article
An attenuated variant of Coxsackievirus B3 preferentially induces immunoregulatory T cells in vivo.
Journal of virology - 1 Nov 1991
Loudon R P, Moraska A F, Huber S A, Schwimmbeck P, Schultheiss P
Abstract excerpt
BALB/c mice infected with the Woodruff variant of coxsackievirus group B type 3 (CVB3W) develop myocarditis mediated by autoimmune cytolytic T lymphocytes. A variant of CVB3W (designated H3-10A1) which infects the myocardium but induces minimal mortality of myocarditis compared to the parental vi...
Topics
- Animals
- Animals, Newborn
- CD4 Antigens
- Coxsackievirus Infections
- Cyclophosphamide
- Cytotoxicity, Immunologic
- Enterovirus B, Human
- Genetic Variation
- Heart
- Immunotherapy, Adoptive
- Mice
- Mice, Inbred BALB C
- Spleen
- T-Lymphocyte Subsets
- T-Lymphocytes