MHC class II-restricted presentation of intracellular antigen.

doi:10.1016/0092-8674(91)90506-t

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Article

MHC class II-restricted presentation of intracellular antigen.

Cell - 22 Feb 1991

Weiss S, Bogen B

Abstract excerpt

An endogenously produced immunoglobulin light chain (lambda 2(315] is processed and presented to T cells in association with major histocompatibility complex (MHC) class II molecules. Using transfectants producing variant forms of lambda 2(315) that are neither expressed on the cell surface nor secreted, we demonstrate that intracellular lambda 2(315), which has never been exported outside of the cell, is the...

Topics

Animals
Antibodies, Monoclonal
Base Sequence
Cell Line
Cell Nucleus
Enhancer Elements, Genetic
Genes, MHC Class II
Genetic Variation
Genetic Vectors
Histocompatibility Antigens Class II
Immunoglobulin Light Chains

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Mice, Inbred BALB C

Molecular Sequence Data

Oligonucleotide Probes

Promoter Regions, Genetic

Receptors, Antigen, B-Cell

Simian virus 40

Source

Open in PubMed

Identifiers

PMID: 1847667
DOI: 10.1016/0092-8674(91)90506-t

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1847667-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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