Article
Naturally-occurring peptide antigens derived from the MHC class-I-restricted processing pathway.
Immunology today - 1 Dec 1991
Rötzschke O, Falk K
Abstract excerpt
The extraction of naturally-processed peptides from MHC class I glycoproteins has paved the way for a major advance in the understanding of the antigen processing pathway that ultimately induces cytotoxic T-cell responses. Here, Olaf Rötzschke and Kirsten Falk review these new developments and di...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Antigen-Presenting Cells
- Antigens
- Antigens, Viral
- Consensus Sequence
- Endopeptidases
- Epitopes
- Graft Rejection
- Histocompatibility Antigens
- Histocompatibility Antigens Class I
- Humans
- Immune Tolerance
- Models, Biological
- Models, Molecular
- Molecular Sequence Data
- Peptide Fragments