Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Natural T-cell ligands that are created by genetic variants can be transferred between cells by extracellular vesicles.

European journal of immunology - 1 Oct 2018

Kremer Anita N, Zonneveld Marijke I, Kremer Andreas E, van der Meijden Edith D, Falkenburg J H Frederik, Wauben Marca H M, Nolte-'t Hoen Esther N M, Griffioen Marieke

Abstract excerpt

CD4 T cells play a central role as helper cells in adaptive immunity. Presentation of exogenous antigens in MHC class II by professional antigen-presenting cells is a crucial step in induction of specific CD4 T cells in adaptive immune responses. For efficient induction of immunity against intracellular threats such as viruses or malignant transformations, antigens from HLA class II-negative infected or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigen Presentation
Share to Antigen-Presenting Cells

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Extracellular Vesicles

Share to Focal Adhesion Kinase 2

Share to Histocompatibility Antigens Class II

Share to Minor Histocompatibility Antigens

Share to Phosphotransferases (Alcohol Group Acceptor)

Share to T-Lymphocytes, Helper-Inducer

Source

Open in PubMed Open full text

Identifiers

PMID: 30011060
DOI: 10.1002/eji.201747152
PMCID: PMC6220790

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Natural T-cell ligands that are created by genetic variants can be transferred between cells by extracellular vesicles.PMID 30011060Read ↗

CAR-T-Derived Extracellular Vesicles: A Promising Development of CAR-T Anti-Tumor TherapySemantic proximity Read ↗

Extracellular Vesicles and Tumor-Immune Escape: Biological Functions and Clinical PerspectivesSemantic proximity Read ↗

Engineered immunomodulatory extracellular vesicles derived from epithelial cells acquire capacity for positive and negative T cell co-stimulation in cancer and autoimmunitySemantic proximity Read ↗

Tumour‐associated antigenic peptides are present in the HLA class I ligandome of cancer cell line derived extracellular vesiclesSemantic proximity Read ↗

Repurposed endogenous virus-like vesicles mediate dendritic cell long-range antigen presentation and T cell activation for enhanced cancer vaccinationSemantic proximity Read ↗

Endo-lysosomal assembly variations among Human Leukocyte Antigen class I (HLA-I) allotypesSemantic proximity Read ↗

Cell membrane patches transfer CAR molecules from a cellular depot to conventional T cells for constructing innovative fused-CAR-T cells without necessitating genetic modificationSemantic proximity Read ↗

Soluble HLA-G and HLA-G Bearing Extracellular Vesicles Affect ILT-2 Positive and ILT-2 Negative CD8 T Cells Complementary.Semantic proximity Read ↗

Emerging role of exosomes in allorecognition and allograft rejectionSemantic proximity Read ↗

Control of dendritic cell cross-presentation by the major histocompatibility complex class I cytoplasmic domain.Semantic proximity Read ↗

Extracellular vesicle-mediated transfer of donor genomic DNA to recipient cells is a novel mechanism for genetic influence between cellsSemantic proximity Read ↗

Vγ9Vδ2 T Cells Concurrently Kill Cancer Cells and Cross-Present Tumor AntigensSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.