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Article

The neuroendocrine circuitry controlled by POMC, MSH, and AGRP.

Handbook of experimental pharmacology - 1 Jan 2012

Biebermann Heike, Kühnen Peter, Kleinau Gunnar, Krude Heiko

Abstract excerpt

Obesity is one of the most challenging health problems worldwide. Over the past few decades, our knowledge concerning mechanisms of weight regulation has increased tremendously leading to the identification of the leptin-melanocortin pathway. The filling level of energy stores is signaled to the brain, and the information is integrated by hypothalamic nuclei, resulting in a well-orchestrated response to food...

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Source

Identifiers

PMID: 22249810
DOI: 10.1007/978-3-642-24716-3_3

Genes

POMC
AGRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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