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Article

Dicer inactivation leads to progressive functional and structural degeneration of the mouse retina.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 7 May 2008

Damiani Devid, Alexander John J, O'Rourke Jason R, McManus Mike, Jadhav Ashutosh P, Cepko Constance L, Hauswirth William W, Harfe Brian D, Strettoi Enrica

Abstract excerpt

MicroRNAs (miRNAs) are small, highly conserved molecules that have been shown to regulate the expression of genes by binding to specific target mRNAs. Dicer, an RNase III endonuclease, is essential for the production and function of mature miRNAs, and removal of Dicer has been shown to disrupt ma...

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Identifiers

PMID: 18463241
DOI: 10.1523/JNEUROSCI.0828-08.2008
PMCID: PMC3325486

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ERG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18463241-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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