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Article

Dicer Plays Essential Roles for Retinal Development by Regulation of Survival and Differentiation

27 Jan 2011

Abstract excerpt

PURPOSE: Much attention has been paid to the roles of microRNA in developmental and biological processes. Dicer plays essential roles in cell survival and proliferation in various organs. We examined the role of Dicer in retinal development using retina-specific conditional knockout of Dicer in mice. METHODS: Dkk3-Cre expressed the Cre gene in retinal progenitor cells from an early embryonic stage. The authors...

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PMID: 21273552
DOI: 10.1167/iovs.10-6428

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