Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Deletion of miR-182 Leads to Retinal Dysfunction in Mice

29 Mar 2019

Abstract excerpt

Purpose: MicroRNA-182 (miR-182) is abundantly expressed in mammalian retinas; however, the association between miR-182 and retinal function remains unclear. In this study, we explored whether miR-182 contributes to functional decline in retinas using a miR-182 depleted mouse. Methods: Electroretinogram (ERG) amplitudes at different ages were measured in miR-182 knockout (KO) mice. The thickness and lamination of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to MicroRNA in disease regulation
Share to Retinal Development and Disorders
Share to Retinal Diseases and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30924851
DOI: 10.1167/iovs.18-24166

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Deletion of miR-182 Leads to Retinal Dysfunction in MicePMID 30924851Read ↗

Roles of miR-204 in retinal development and maintenanceSemantic proximity Read ↗

Dicer inactivation leads to progressive functional and structural degeneration of the mouse retina.Semantic proximity Read ↗

Ocular Phenotyping of Knockout Mice Identifies Genes Associated With Late Adult Retinal Phenotypes.Semantic proximity Read ↗

miR-183/96/182 cluster is an important morphogenetic factor targeting <i>PAX6</i> expression in differentiating human retinal organoidsSemantic proximity Read ↗

Exploring miRNAs as modulators in retinal degeneration : potential therapeutic tools for inherited retinal dystrophiesSemantic proximity Read ↗

DICER1 is essential for survival of postmitotic rod photoreceptor cells in miceSemantic proximity Read ↗

Light-Responsive MicroRNAs in Human Retinal Tissue are Differentially Regulated by Distinct Wavelengths of LightSemantic proximity Read ↗

Loss-of-function approach using mouse retinal explants showed pivotal roles of Nmnat2 in early and middle stages of retinal development.Semantic proximity Read ↗

Monitoring mouse retinal degeneration with high-resolution spectral-domain optical coherence tomographySemantic proximity Read ↗

Functional microRNA targetome undergoes degeneration-induced shift in the retinaSemantic proximity Read ↗

Disease-associated microRNA, miR-9-2, regulates timing of retinal progenitor cell competence and maintenance of Müller glial identitySemantic proximity Read ↗

Zebrafish dou yan mutation causes patterning defects and extensive cell death in the retina.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.