Article
Initiation of DNA replication by a third parallel DNA strand bound in a triple-helix manner leads to strand invasion.
Biochemistry - 27 May 2008
Lestienne Patrick P, Boudsocq François, Bonnet Jacques E
Abstract excerpt
According to current knowledge, DNA polymerases accommodate only two polynucleotide strands in their catalytic site: the template and the primer to be elongated. Here we show that in addition to these two polynucleotide strands, HIV-1 and AMV reverse transcriptases, human DNA polymerases beta, ga...
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