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Article

Two MTHFR polymorphisms, maternal B-vitamin intake, and CHDs.

Birth defects research. Part A, Clinical and molecular teratology - 1 Jun 2008

van Driel Lydi M J W, Verkleij-Hagoort Anna C, de Jonge Robert, Uitterlinden André G, Steegers Eric A P, van Duijn Cornelia M, Steegers-Theunissen Régine P M

Abstract excerpt

BACKGROUND: The methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms are associated with complex congenital malformations. Whether these polymorphisms are associated with CHDs is not clear. We studied both MTHFR polymorphisms, folate and vitamin B2 by maternal food intake and supplements, and CHD risk. METHODS: A case-control family study was conducted in a European population in the...

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Source

Identifiers

PMID: 18452180
DOI: 10.1002/bdra.20463

Genes

MTHFR

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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