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Periconception Red Blood Cell Folate and Offspring Congenital Heart Disease

22 Aug 2022

Abstract excerpt

BACKGROUND: Periconception folic acid supplementation has been suggested to protect against congenital heart disease (CHD), but the association between maternal red blood cell (RBC) folate, the gold-standard biomarker of folate exposure, and subsequent offspring CHD risk is lacking. OBJECTIVE: To quantify the association between periconception maternal RBC folate and offspring CHD risk. DESIGN: Prospective,...

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PMID: 35994746
DOI: 10.7326/m22-0741

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