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Article

Maternal folate-related gene environment interactions and congenital heart defects.

Obstetrics and gynecology - 1 Aug 2010

Hobbs Charlotte A, Cleves Mario A, Karim Mohammad A, Zhao Weizhi, MacLeod Stewart L

Abstract excerpt

OBJECTIVE: To investigate whether women with congenital heart defect (CHD)-affected pregnancies were more likely to have functional single-nucleotide polymorphisms in genes encoding enzymes in folate-dependent pathways. METHODS: A population-based case-control study of 572 women with CHD-affected pregnancies and 363 women in the control group was conducted. DNA samples were genotyped for single-nucleotide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Methylenetetrahydrofolate Reductase (NADPH2)

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Source

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Identifiers

PMID: 20664391
DOI: 10.1097/AOG.0b013e3181e80979
PMCID: PMC3027124

Genes

BHMT
MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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