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Article

Farnesoid X Receptor Protects Liver Cells from Apoptosis Induced by Serum Deprivation in Vitro and Fasting in Vivo

25 Apr 2008

Abstract excerpt

The farnesoid X receptor (FXR) is a key metabolic regulator in the liver by maintaining the homeostasis of liver metabolites. Recent findings suggest that FXR may have a much broader function in liver physiology and pathology. In the present work, we identify a novel role of FXR in protecting liver cell from apoptosis induced by nutritional withdrawal including serum deprivation in vitro or starvation in vivo....

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Share to Drug-Induced Hepatotoxicity and Protection
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Identifiers

PMID: 18436567
DOI: 10.1210/me.2007-0527

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