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The emerging roles of liver X receptors and their ligands in cancer

26 Aug 2015

Abstract excerpt

INTRODUCTION: Liver X receptors (LXRs) are nuclear receptors with well-known functions in cholesterol transport, fatty acid and glucose metabolism, and modulation of immune responses. Natural and synthetic ligands have been identified and are under development for the treatment of metabolic and inflammatory conditions and diseases. There is mounting evidence pointing to functional roles for LXRs in a variety of...

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PMID: 26788589
DOI: 10.1517/14728222.2015.1081169

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